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Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway

Abstract The lack of knowledge about the mechanism of hyperoxia-induced intestinal injury has attracted considerable attention, due to the potential for this condition to cause neonatal complications. This study aimed to explore the relationship between hyperoxia-induced oxidative damage and ferropt...

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Principais autores: Yanping Liu, Tianming Li, Changping Niu, Zhengwei Yuan, Siyu Sun, Dongyan Liu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-01-01
coleção:Molecular Medicine
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Acesso em linha:https://doi.org/10.1186/s10020-024-00993-7
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