Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway

Abstract The lack of knowledge about the mechanism of hyperoxia-induced intestinal injury has attracted considerable attention, due to the potential for this condition to cause neonatal complications. This study aimed to explore the relationship between hyperoxia-induced oxidative damage and ferropt...

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Autores principales:	Yanping Liu, Tianming Li, Changping Niu, Zhengwei Yuan, Siyu Sun, Dongyan Liu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-01-01
Colección:	Molecular Medicine
Materias:	Hyperoxia Intestinal epithelial cells Ferroptosis COX-2/PGE2/EP2 pathway Inflammatory
Acceso en línea:	https://doi.org/10.1186/s10020-024-00993-7
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