Low T cell diversity associates with poor outcome in bladder cancer: A comprehensive longitudinal analysis of the T cell receptor repertoire

Summary: T cells are crucial effector cells in the endogenous defense against cancer, yet the clinical impact of their quantity, diversity, and dynamics remains underexplored. Here, we investigate the clinical relevance of the T cell receptor (TCR) repertoire in patients with bladder cancer. In adva...

Descripció completa

Dades bibliogràfiques

Autors principals:	Asbjørn Kjær, Nanna Kristjánsdóttir, Randi Istrup Juul, Iver Nordentoft, Karin Birkenkamp-Demtröder, Johanne Ahrenfeldt, Trine Strandgaard, Deema Radif, Darren Hodgson, Christopher Abbosh, Hugo J.W.L. Aerts, Mads Agerbæk, Jørgen Bjerggaard Jensen, Nicolai J. Birkbak, Lars Dyrskjøt
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-05-01
Col·lecció:	Cell Reports Medicine
Matèries:	T cell receptors TCR sequencing single-cell sequencing bladder cancer muscle-invasive bladder cancer biomarkers
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2666379125001740
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!