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The design and development of covalent protein-protein interaction inhibitors for cancer treatment

Abstract Protein-protein interactions (PPIs) are central to a variety of biological processes, and their dysfunction is implicated in the pathogenesis of a range of human diseases, including cancer. Hence, the inhibition of PPIs has attracted significant attention in drug discovery. Covalent inhibit...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Sha-Sha Cheng, Guan-Jun Yang, Wanhe Wang, Chung-Hang Leung, Dik-Lung Ma
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2020-03-01
Rangatū:Journal of Hematology & Oncology
Ngā marau:
Urunga tuihono:http://link.springer.com/article/10.1186/s13045-020-00850-0
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