The design and development of covalent protein-protein interaction inhibitors for cancer treatment
Abstract Protein-protein interactions (PPIs) are central to a variety of biological processes, and their dysfunction is implicated in the pathogenesis of a range of human diseases, including cancer. Hence, the inhibition of PPIs has attracted significant attention in drug discovery. Covalent inhibit...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2020-03-01
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| Collection: | Journal of Hematology & Oncology |
| Sujets: | |
| Accès en ligne: | http://link.springer.com/article/10.1186/s13045-020-00850-0 |
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