NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis

Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism and adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. NADPH is a central co-factor for both lipid and redox...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Didem Ilter, Stanislav Drapela, Tanya Schild, Nathan P. Ward, Emma Adhikari, Vivien Low, John Asara, Thordur Oskarsson, Eric K. Lau, Gina M. DeNicola, Melanie R. McReynolds, Ana P. Gomes
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-05-01
Schriftenreihe:	Redox Biology
Schlagworte:	Metastasis Breast cancer Redox NADPH NADK
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2213231723000289
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