Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation
Abstract Synucleinopathies refer to a group of disorders characterized by SNCA/α-synuclein (α-Syn)-containing cytoplasmic inclusions and neuronal cell loss in the nervous system including the cortex, a common feature being cognitive impairment. Still, the molecular pathogenesis of cognitive decline...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2024-03-01
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| Serier: | Molecular Brain |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s13041-024-01086-6 |
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