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Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions

Background Research on mesenchymal stromal cells has created high expectations for a variety of therapeutic applications. Extensive propagation to yield enough mesenchymal stromal cells for therapy may result in replicative senescence and thus hamper long-term functionality in vivo. Highly variable...

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Autori principali: Katharina Schallmoser, Christina Bartmann, Eva Rohde, Simone Bork, Christian Guelly, Anna C. Obenauf, Andreas Reinisch, Patrick Horn, Anthony D. Ho, Dirk Strunk, Wolfgang Wagner
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2010-06-01
Serie:Haematologica
Accesso online:https://haematologica.org/article/view/5621
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