Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions
Background Research on mesenchymal stromal cells has created high expectations for a variety of therapeutic applications. Extensive propagation to yield enough mesenchymal stromal cells for therapy may result in replicative senescence and thus hamper long-term functionality in vivo. Highly variable...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ferrata Storti Foundation
2010-06-01
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| Serier: | Haematologica |
| Online adgang: | https://haematologica.org/article/view/5621 |
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