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Evaluating role of TNF-α in tyrosine kinase inhibitors-treated chronic myeloid leukemia

PurposeChronic Myeloid Leukemia (CML) is characterized by the BCR-ABL1 fusion gene and is effectively managed with tyrosine kinase inhibitors (TKIs). However, therapeutic resistance and the persistence of leukemic stem cells pose challenges to achieving long-term remission. Tumor Necrosis Factor-alp...

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Kaydedildi:
Asıl Yazarlar: Gratial Theres Joseph, Sandeep Kumar Swain, Himanshu Dhanda, Neetu Kushwaha, Priti Kumari, Mahek Pravin Khushalani, Rakesh Kumar, Baseer Noor, Sufian Zaheer, Aditi Jain, Ankur Jain, Sumita Chaudhry, Pranay Tanwar, Amitabh Singh, Bhavika Rishi, Aroonima Misra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2026-02-01
Seri Bilgileri:Frontiers in Hematology
Konular:
BCR-ABL1
chronic myeloid leukemia (CML)
cytokine biomarker
ELISA
imatinib
qRT-PCR
Online Erişim:https://www.frontiersin.org/articles/10.3389/frhem.2026.1709697/full
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