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Cadmium activation of wild-type and constitutively active estrogen receptor alpha

The estrogen receptor alpha (ERα) plays a central role in the etiology, progression, and treatment of breast cancers. Constitutively activating somatic mutations Y537S and D538G, in the ligand binding domain (LBD) of ESR1, are associated with acquired resistance to endocrine therapies. We have previ...

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Xehetasun bibliografikoak
Egile Nagusiak: John B. Psaltis, Qiaochu Wang, Gai Yan, Reem Gahtani, Nanxi Huang, Bassem R. Haddad, Mary Beth Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2024-08-01
Saila:Frontiers in Endocrinology
Gaiak:
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fendo.2024.1380047/full
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