Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial [version 2; referees: 3 approved, 1 approved with reservations]

Background: Worldwide, traumatic brain injury (TBI) kills or hospitalises over 10 million people each year. Early intracranial bleeding is common after TBI, increasing the risk of death and disability. Tranexamic acid reduces blood loss in surgery and death due to bleeding in trauma patients with ex...

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Principais autores:	Ian Roberts, Antonio Belli, Amy Brenner, Rizwana Chaudhri, Bukola Fawole, Tim Harris, Rashid Jooma, Abda Mahmood, Temitayo Shokunbi, Haleema Shakur, CRASH-3 trial collaborators
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wellcome 2018-09-01
coleção:	Wellcome Open Research
Acesso em linha:	https://wellcomeopenresearch.org/articles/3-86/v2
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