Clinical advances and challenges in targeting FGF/FGFR signaling in lung cancer
Abstract Fibroblast growth factors (FGFs) and their receptors regulate numerous cellular processes, such as metabolism and signal transduction, but can also drive tumorigenesis. Specifically, in lung cancer, the overexpression of FGFs, as well as the amplification, mutation and fusion of FGFR genes,...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2024-11-01
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| coleção: | Molecular Cancer |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12943-024-02167-9 |
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