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Clinical advances and challenges in targeting FGF/FGFR signaling in lung cancer

Abstract Fibroblast growth factors (FGFs) and their receptors regulate numerous cellular processes, such as metabolism and signal transduction, but can also drive tumorigenesis. Specifically, in lung cancer, the overexpression of FGFs, as well as the amplification, mutation and fusion of FGFR genes,...

詳細記述

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書誌詳細
主要な著者: Mei Peng, Jun Deng, Xiangping Li
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2024-11-01
シリーズ:Molecular Cancer
主題:
オンライン・アクセス:https://doi.org/10.1186/s12943-024-02167-9
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