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Aerosolizable Lipid Nanoparticles for Pulmonary Delivery of mRNA through Design of Experiments

Messenger RNA is a class of promising nucleic acid therapeutics to treat a variety of diseases, including genetic diseases. The development of a stable and efficacious mRNA pulmonary delivery system would enable high therapeutic concentrations locally in the lungs to improve efficacy and limit poten...

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Hlavní autoři: Hairui Zhang, Jasmim Leal, Melissa R. Soto, Hugh D. C. Smyth, Debadyuti Ghosh
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-10-01
Edice:Pharmaceutics
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On-line přístup:https://www.mdpi.com/1999-4923/12/11/1042
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