Genetic risk for neurodevelopmental disorders as a potential factor affecting antipsychotic responsiveness in schizophrenia: a postmortem brain study

IntroductionSchizophrenia (SCZ) is a highly heritable neuropsychiatric disorder. Its genomic architecture reportedly overlaps with that of neurodevelopmental disorders, such as attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). However, the effect of genomic risk for...

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Bibliographic Details

Main Authors:	Kazusa Miyahara, Mizuki Hino, Risa Shishido, Atsuko Nagaoka, Hideomi Hamasaki, Akiyoshi Kakita, Hiroaki Tomita, Yasuto Kunii
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-04-01
Series:	Frontiers in Psychiatry
Subjects:	attention deficit hyperactivity disorder autism spectrum disorder polygenic risk score schizophrenia treatment resistance
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1812198/full
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