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Impact of Confounding Factors in Human Postmortem Brain Tissues on Gene Expression Profiles: A Comparison of Patients With Schizophrenia, Bipolar Disorder, and Nonpsychiatric Controls

ABSTRACT Controlling for confounding factors in postmortem brain studies of psychiatric disorders is crucial, particularly in gene expression analyses. Potential confounding factors include sex, age at death, medication history, agonal state, postmortem interval (PMI), tissue storage duration, tissu...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Masataka Hatano, Atsuko Nagaoka, Kazusa Miyahara, Yuto Hosogai, Risa Shishido, Hideomi Hamasaki, Mizuki Hino, Akiyoshi Kakita, Hiroaki Tomita, Yasuto Kunii, Itaru Miura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2025-09-01
Schriftenreihe:Neuropsychopharmacology Reports
Schlagworte:
bipolar disorder
confounding factor
postmortem brain
RNA‐seq
schizophrenia
Online-Zugang:https://doi.org/10.1002/npr2.70053
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