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Loss of CDS1 impairs the tumorigenic characteristics of nasopharyngeal carcinoma by modulating lipid metabolism

The accumulation of lipid droplets (LDs) enhancing nasopharyngeal carcinoma (NPC) cell migration. We reveals that CDP-diacylglycerol synthase 1 (CDS1), an inhibitor of LDs formation, is significantly downregulated in NPC. Restoring CDS1 expression suppresses NPC cell growth, colony formation, tumori...

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Kaydedildi:
Asıl Yazarlar: Yifang Wang, Limei Li, Liudmila Matskova, Lixian Deng, Danping Li, Yi Huang, Haili Liang, Wen Wang, Ziyuan Liang, Jiaming Su, Weilin Zhao, Tingting Huang, Jiemei Chu, Zhe Zhang, Xue Xiao, Xiaoying Zhou
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2025-12-01
Seri Bilgileri:Cell Adhesion & Migration
Konular:
Nasopharyngeal carcinoma
CDP-diacylglycerol synthase 1
lipid droplets
NF-κB signaling pathway
inflammatory cytokines
Online Erişim:https://www.tandfonline.com/doi/10.1080/19336918.2025.2520629
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