Loss of CDS1 impairs the tumorigenic characteristics of nasopharyngeal carcinoma by modulating lipid metabolism

The accumulation of lipid droplets (LDs) enhancing nasopharyngeal carcinoma (NPC) cell migration. We reveals that CDP-diacylglycerol synthase 1 (CDS1), an inhibitor of LDs formation, is significantly downregulated in NPC. Restoring CDS1 expression suppresses NPC cell growth, colony formation, tumori...

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Detalhes bibliográficos

Principais autores:	Yifang Wang, Limei Li, Liudmila Matskova, Lixian Deng, Danping Li, Yi Huang, Haili Liang, Wen Wang, Ziyuan Liang, Jiaming Su, Weilin Zhao, Tingting Huang, Jiemei Chu, Zhe Zhang, Xue Xiao, Xiaoying Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2025-12-01
coleção:	Cell Adhesion & Migration
Assuntos:	Nasopharyngeal carcinoma CDP-diacylglycerol synthase 1 lipid droplets NF-κB signaling pathway inflammatory cytokines
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/19336918.2025.2520629
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