Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients.

BACKGROUND: In type 1 von Willebrand Disease (VWD) patients, von Willebrand Factor (VWF) levels and bleeding symptoms are highly variable. Recently, the association between genetic variations in STXBP5 and STX2 with VWF levels has been discovered in the general population. We assessed the relationsh...

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Detalhes bibliográficos

Principais autores:	Janine E van Loon, Yvonne V Sanders, Eva M de Wee, Marieke J H A Kruip, Moniek P M de Maat, Frank W G Leebeek
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3391281?pdf=render
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