Synthesis of new quinazoline-linked fused imidazole-oxazole conjugates; evaluation of anticancer activity, molecular docking, DFT and ADMET studies

A novel series of quinazoline-linked fused imidazole-oxazole conjugates (9a-n) were synthesized and evaluated for their anticancer activity against two breast cancer cell lines such as MDA-MB231 and MCF-7 using the MTT assay. The erlotinib used as a standard reference drug. The anticancer activity o...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Devula Venkata. Nagarajesh, Dasari. Gouthami, Kandala. Satyanarayana, Marupati. Siddhartha, Aitipamula. Dayanand, Dharanipathi. Venkateshwar Rao, Amrutha. Vasantha, Palabindela. Rambabu, Bandari. Srinivas
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-05-01
Edice:	Results in Chemistry
Témata:	Quinazoline-linked fused imidazole-oxazole conjugates In vitro anticancer In vitro tyrosine kinase EGFR inhibitory activity DFT studies Molecular docking studies
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211715626000901
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!