Synthesis of new quinazoline-linked fused imidazole-oxazole conjugates; evaluation of anticancer activity, molecular docking, DFT and ADMET studies

A novel series of quinazoline-linked fused imidazole-oxazole conjugates (9a-n) were synthesized and evaluated for their anticancer activity against two breast cancer cell lines such as MDA-MB231 and MCF-7 using the MTT assay. The erlotinib used as a standard reference drug. The anticancer activity o...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Devula Venkata. Nagarajesh, Dasari. Gouthami, Kandala. Satyanarayana, Marupati. Siddhartha, Aitipamula. Dayanand, Dharanipathi. Venkateshwar Rao, Amrutha. Vasantha, Palabindela. Rambabu, Bandari. Srinivas
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2026-05-01
Sarja:	Results in Chemistry
Aiheet:	Quinazoline-linked fused imidazole-oxazole conjugates In vitro anticancer In vitro tyrosine kinase EGFR inhibitory activity DFT studies Molecular docking studies
Linkit:	http://www.sciencedirect.com/science/article/pii/S2211715626000901
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