The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels

Background and purpose: Ivabradine is clinically administered to lower the heart rate, proposedly by inhibiting hyperpolarization-activated cyclic nucleotide-gated cation channels in the sinoatrial node. Recent evidence suggests that voltage-gated sodium channels (VGSC) are inhibited within the same...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Benjamin Hackl, Peter Lukacs, Janine Ebner, Krisztina Pesti, Nicholas Haechl, Mátyás C Földi, Elena Lilliu, Klaus Schicker, Helmut Kubista, Anna Stary-Weinzinger, Karlheinz Hilber, Arpad Mike, Hannes Todt, Xaver Koenig
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-05-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	ivabradine S16257 voltage-gated sodium channel conduction cell ventricular cardiomyocyte atypical inhibitor
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fphar.2022.809802/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!