Quantitative Evaluation of Intraventricular Delivery of Therapeutic Neural Stem Cells to Orthotopic Glioma

Neural stem cells (NSCs) are inherently tumor-tropic, which allows them to migrate through normal tissue and selectively localize to invasive tumor sites in the brain. We have engineered a clonal, immortalized allogeneic NSC line (HB1.F3.CD21; CD-NSCs) that maintains its stem-like properties, a norm...

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Autori principali:	Margarita Gutova, Linda Flores, Vikram Adhikarla, Lusine Tsaturyan, Revathiswari Tirughana, Soraya Aramburo, Marianne Metz, Joanna Gonzaga, Alexander Annala, Timothy W. Synold, Jana Portnow, Russell C. Rockne, Karen S. Aboody
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2019-02-01
Serie:	Frontiers in Oncology
Soggetti:	glioma neural stem cells NSCs intraventricular administration therapeutic drug delivery
Accesso online:	https://www.frontiersin.org/article/10.3389/fonc.2019.00068/full
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