Integrative network toxicology, transcriptomic, and molecular docking approaches to elucidate the toxicity and mechanisms of bisphenol A in stroke

Abstract Background Bisphenol A (BPA), a widespread environmental endocrine disruptor, has raised concerns for its neurotoxic effects, yet its molecular role in stroke remains unclear. Methods BPA target genes were retrieved from ChEMBL, DrugBank, and SwissTargetPrediction. Differentially expressed...

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Ngā kaituhi matua:	Zhonghui Wen, Bin Hu, Qiongfang Zhang, Zhifu Sun, Hai Wang, Kun Zhang, Jingchun Pei, Ziyu Chen
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2025-12-01
Rangatū:	BMC Pharmacology and Toxicology
Ngā marau:	Bisphenol A Stroke Network toxicology Molecular docking Mitochondrial respiratory chain complex I
Urunga tuihono:	https://doi.org/10.1186/s40360-025-01076-x
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!