A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative helicase

DNA replication is mediated by a multi-protein complex known as the replisome. With the hexameric MCM (minichromosome maintenance) replicative helicase at its core, the replisome splits the parental DNA strands, forming replication forks (RFs), where it catalyses coupled leading and lagging strand D...

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Detalles Bibliográficos

Principais autores:	Benoît Falquet, Ulrich Rass
Formato:	Artigo
Idioma:	Inglês
Publicado:	Shared Science Publishers OG 2017-01-01
Series:	Microbial Cell
Assuntos:	replication stress DNA repair genome stability replication fork restart anaphase bridges chromosome non-disjunction structure-specific nucleases
Acceso en liña:	http://microbialcell.com/researcharticles/a-new-role-for-holliday-junction-resolvase-yen1-in-processing-dna-replication-intermediates-exposes-dna2-as-an-accessory-replicative-helicase/
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