Beyond glycemic control: the cardiac and hepatic benefits of SGLT2 and DPP-4 inhibitors in mitigating chronic cadmium-induced inflammation, oxidative/nitrative stress, apoptosis and fibrosis

BackgroundCadmium (Cd) is a hazardous ecological contaminant implicated in substantial oxidative stress (OS), nitrative stress, inflammation, apoptosis and fibrosis, particularly in the heart and liver.ObjectiveThis study aims to contrast the protective effects of “Canagliflozin; Cana” versus “Sitag...

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Principais autores:	Fatma E. Hassan, MennaAllah M. Hassanien, Asmaa Selmy, Lamiaa Mohamed Mahmoud, Amal Darwish, Basant A. Aldreny
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
coleção:	Frontiers in Physiology
Assuntos:	cadmium DPP-4i heart liver SGLT2i
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphys.2025.1752370/full
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