The SGLT2i “canagliflozin” and the DPP-4i “sitagliptin” mitigate hypertensive nephropathy in adult male rats by modulating the Ang II/RAGE/Nox4/NLRP3 cascade

BackgroundHypertensive nephropathy (HN) with progressive renal damage is a common consequence of arterial hypertension (HTN). This study addresses the renoprotective attributes of the sodium-glucose cotransporter-2 inhibitor canagliflozin (Cana) and the dipeptidyl peptidase-4 inhibitor sitagliptin (...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Fatma E. Hassan, Fatma Al-Zahraa Nabil Al-Shahed, Asmaa Selmy, Lamiaa Mohamed Mahmoud, Basant A. Aldreny
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-06-01
Serija:	Frontiers in Physiology
Teme:	angiotensin II canagliflozin DPP-4i hypertension nephropathy RAGE
Online dostop:	https://www.frontiersin.org/articles/10.3389/fphys.2026.1885144/full
Oznake:	Označite Brez oznak, prvi označite!