IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis

Abstract Background Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The glycosylation status of immunoglobulin G (IgG) is altered in RA and influenced by MTX treatment. We aimed to further investigate if...

Полное описание

Библиографические подробности

Главные авторы:	Susanna L. Lundström, Aase H. Hensvold, Dorothea Rutishauser, Lars Klareskog, A. Jimmy Ytterberg, Roman A. Zubarev, Anca I. Catrina
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2017-08-01
Серии:	Arthritis Research & Therapy
Предметы:	Immunoglobulin Glycosylation Rheumatoid arthritis Methotrexate Complement Biomarker
Online-ссылка:	http://link.springer.com/article/10.1186/s13075-017-1389-7
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!