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Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma

Capicua (CIC)-rearranged sarcomas are an aggressive subset of undifferentiated round cell sarcomas. CIC::DUX4, the proto-typical CIC fusion oncoprotein is associated with rapid clinical progression and chemotherapy resistance leading to poor clinical outcomes. Recent studies have identified addition...

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Auteurs principaux: Rovingaile Kriska M. Ponce, Cuyler Luck, Ross A. Okimoto
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2024-05-01
Collection:Frontiers in Cell and Developmental Biology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fcell.2024.1416697/full
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