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Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates

Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide. Chikungunya virus is an emerging disease problem that is b...

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Kaydedildi:
Asıl Yazarlar: Chonticha Saisawang, Pornpan Sillapee, Kwanhathai Sinsirimongkol, Sukathida Ubol, Duncan R. Smith, Albert J. Ketterman
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press 2015-05-01
Seri Bilgileri:Bioscience Reports
Konular:
alphavirus
chikungunya virus
cysteine protease
non-structural protein 2 (nsP2)
Online Erişim:http://www.bioscirep.org/bsr/035/e196/bsr035e196.htm
Etiketler: Etiketle
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