Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates

Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide. Chikungunya virus is an emerging disease problem that is b...

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Hlavní autoři:	Chonticha Saisawang, Pornpan Sillapee, Kwanhathai Sinsirimongkol, Sukathida Ubol, Duncan R. Smith, Albert J. Ketterman
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Portland Press 2015-05-01
Edice:	Bioscience Reports
Témata:	alphavirus chikungunya virus cysteine protease non-structural protein 2 (nsP2)
On-line přístup:	http://www.bioscirep.org/bsr/035/e196/bsr035e196.htm
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