Lysosome stress response and mitochondria injury are the earliest detectable alteration in FSGS
Abstract Focal segmental glomerulosclerosis (FSGS) is a histopathologic lesion caused by a dysfunction and loss of podocytes. Podocytes as postmitotic cells, rely on lysosomes to maintain their structural and functional integrity and on mitochondria to adapt their metabolic needs. The importance of...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2025-10-01
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| Col·lecció: | Scientific Reports |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1038/s41598-025-22622-x |
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