Tumor-derived extracellular vesicles mediate cell-specific uptake and facilitate enhanced doxorubicin delivery in breast cancer

BackgroundChemotherapy suppresses tumor growth and metastasis, but its efficacy is limited by non-specificity, systemic toxicity, poor accumulation and side effects. Extracellular vesicles (EVs) derived from cells have recently been tested for carrying drugs due to their biocompatibility, stability,...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Dhananjay B. Alagundagi, Mahima Rachel Thomas, Vinay C. Sangamesh, Vinay Kumar J Rajendra, Vijith V. Shetty, Shama Prasada Kabekkodu, Praveenkumar Shetty, Prakash Patil
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
coleção:	Frontiers in Pharmacology
Assuntos:	breast cancer cellular uptake doxorubicin drug delivery extracellular vesicles nanocarriers
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1744895/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!