Tumor-derived extracellular vesicles mediate cell-specific uptake and facilitate enhanced doxorubicin delivery in breast cancer

BackgroundChemotherapy suppresses tumor growth and metastasis, but its efficacy is limited by non-specificity, systemic toxicity, poor accumulation and side effects. Extracellular vesicles (EVs) derived from cells have recently been tested for carrying drugs due to their biocompatibility, stability,...

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Principais autores:	Dhananjay B. Alagundagi, Mahima Rachel Thomas, Vinay C. Sangamesh, Vinay Kumar J Rajendra, Vijith V. Shetty, Shama Prasada Kabekkodu, Praveenkumar Shetty, Prakash Patil
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-01-01
Serija:	Frontiers in Pharmacology
Teme:	breast cancer cellular uptake doxorubicin drug delivery extracellular vesicles nanocarriers
Online dostop:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1744895/full
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