Retinal fingerprints of ALS in patients: Ganglion cell apoptosis and TDP-43/p62 misplacement

IntroductionAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neuron function. Although ophthalmic deficits are not considered a classic symptom of ALS, recent studies suggest that changes in retinal cells, similar to those in the...

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Hlavní autoři:	Natalia Pediconi, Ylenia Gigante, Silvia Cama, Martina Pitea, Lorenza Mautone, Giancarlo Ruocco, Silvia Ghirga, Silvia Di Angelantonio
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-03-01
Edice:	Frontiers in Aging Neuroscience
Témata:	retina ALS neurodegeneration biomarkers protein inclusions neurons
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1110520/full
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