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Deleterious and protective effects of epothilone-D alone and in the context of amyloid β- and tau-induced alterations

Amyloid-β (Aβ) and hyperphosphorylated tau (P-tau) are Alzheimer’s disease (AD) biomarkers that interact in a complex manner to induce most of the cognitive and brain alterations observed in this disease. Since the neuronal cytoskeleton is a common downstream pathological target of tau and Aβ, which...

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Principais autores: Ángel Abdiel Robles-Gómez, Benito Ordaz, Jonathan-Julio Lorea-Hernández, Fernando Peña-Ortega
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2023-10-01
叢編:Frontiers in Molecular Neuroscience
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1198299/full
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