Deleterious and protective effects of epothilone-D alone and in the context of amyloid β- and tau-induced alterations

Amyloid-β (Aβ) and hyperphosphorylated tau (P-tau) are Alzheimer’s disease (AD) biomarkers that interact in a complex manner to induce most of the cognitive and brain alterations observed in this disease. Since the neuronal cytoskeleton is a common downstream pathological target of tau and Aβ, which...

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Principais autores:	Ángel Abdiel Robles-Gómez, Benito Ordaz, Jonathan-Julio Lorea-Hernández, Fernando Peña-Ortega
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2023-10-01
סדרה:	Frontiers in Molecular Neuroscience
נושאים:	Alzheimer’s disease tau and phospho-tau protein amyloid - β microtubule therapeutic epothilone-D
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1198299/full
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