Plasma proteomics in patients with von Willebrand disease and hemophilia A highlights von Willebrand factor as main determinant of response to desmopressin treatment

Background: Desmopressin, 1-deamino-8-D-arginin vasopressin (DDAVP), is a treatment option for people with von Willebrand disease (VWD) and hemophilia A (HA) with a large interindividual variation in response. DDAVP elicits the release of von Willebrand Factor (VWF) from endothelial cells, thereby i...

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主要な著者:	Jessica del Castillo Alferez, Eva R. Smit, Alexander B. Meijer, Karin Fijnvandraat, Marieke J.H.A. Kruip, Tirsa T. van Duijl, Maartje van den Biggelaar
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2025-03-01
シリーズ:	Research and Practice in Thrombosis and Haemostasis
主題:	DDAVP hemophilia A mass spectrometry proteomics von Willebrand Disease
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2475037925000627
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