Membrane protein CRISPR screen identifies RPSA as an essential host factor for porcine epidemic diarrhea virus replication

ABSTRACT Porcine epidemic diarrhea, caused by porcine epidemic diarrhea virus (PEDV), is one of the most devastating diseases in the global pig industry due to its high mortality rate in piglets. The host factors required for PEDV replication, including receptors, remain poorly understood. Here, we...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu Zhao, Guanghao Guo, Yumei Sun, Mengjia Zhang, Gan Yang, Zhongzhu Liu, Yanbin Song, Ahmed H. Ghonaim, Ningning Ma, Mengdi Zhang, Anan Jongkaewwattana, Qigai He, Wentao Li
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2025-08-01
Seri Bilgileri:Journal of Virology
Konular:
Porcine epidemic diarrhea virus
CRISPR/Cas9
RPSA
ERK1/2 pathway
lipid metabolism
aminopeptidase N
Online Erişim:https://journals.asm.org/doi/10.1128/jvi.00649-25
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