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Lipid-Lowering Effects of Ethyl 2-Phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in Rodents

A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yield the series listed below. Selected pyrrole deri...

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Principais autores: Bruce S. Burnham, John T. Gupton, Keith Krumpe, John R. Lukens, Robert B. Miller, Joshua D. Berkowitz, Bryan J. McCranor, Kam Suet Lam, Josephine Glersaye, Ulander Miott, Brett M. Taylor, Donna L. Wilson, Shahzad Rifat, Gerard A. Dalglish, Daniel C. Smith, Michael A. Evans, Anthony Argenti, Adam Getzel, Kathy O'Toole-Colin, Justin M. Holub
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2004-02-01
coleção:Molecules
Assuntos:
Pyrrole
hypolipidemia
cholesterol
triglyceride
Acesso em linha:http://www.mdpi.com/1420-3049/9/3/134/
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