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Pyrrole and Fused Pyrrole Compounds with Bioactivity against Inflammatory Mediators

A new series of pyrrolopyridines and pyrrolopyridopyrimidines have been synthesized from aminocyanopyrroles. The synthesized compounds have been characterized by FTIR, 1H-NMR and mass spectroscopy. The final compounds have been screened for in vitro pro-inflammatory cytokine inhibitory and in vivo a...

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Principais autores: Samar Said Fatahala, Sherifa Hasabelnaby, Ayman Goudah, Ghada I. Mahmoud, Rania Helmy Abd-El Hameed
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-03-01
coleção:Molecules
Assuntos:
pyrroles
pyrrolopyridines
synthesis
anti-inflammatory assay
cytokine inhibitors
docking study
Acesso em linha:http://www.mdpi.com/1420-3049/22/3/461
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