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Metabolic insights into phosphofructokinase inhibition in bloodstream-form trypanosomes

Previously, we reported the development of novel small molecules that are potent inhibitors of the glycolytic enzyme phosphofructokinase (PFK) of Trypanosoma brucei and related protists responsible for serious diseases in humans and domestic animals. Cultured bloodstream-form trypanosomes, which are...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Zandile Nare, Tessa Moses, Karl Burgess, Achim Schnaufer, Malcolm D. Walkinshaw, Paul A. M. Michels
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2023-02-01
Rangatū:Frontiers in Cellular and Infection Microbiology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1129791/full
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