Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha

Abstract Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD) degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown markedly higher expression in degenerated human disc tissue compared with healthy controls. Anti‐inflammatory treatm...

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主要な著者:	Jie Du, Judith‐J. Pfannkuche, Gernot Lang, Sonja Häckel, Laura B. Creemers, Mauro Alini, Sibylle Grad, Zhen Li
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2020-09-01
シリーズ:	JOR Spine
主題:	3R cytokines inflammation intervertebral disc regeneration spine
オンライン･アクセス:	https://doi.org/10.1002/jsp2.1104
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