Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis

Abstract Background Mesenchymal stromal cells (MSCs) have been introduced as promising cell source for regenerative medicine. Besides their multilineage differentiation capacity, MSCs release a wide spectrum of bioactive factors. This secretome holds immunomodulatory and regenerative capacities. In...

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Bibliografische Detailangaben

Hauptverfasser:	Sebastian Wangler, Amir Kamali, Christina Wapp, Karin Wuertz-Kozak, Sonja Häckel, Claudia Fortes, Lorin M. Benneker, Lisbet Haglund, R. Geoff Richards, Mauro Alini, Marianna Peroglio, Sibylle Grad
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-01-01
Schriftenreihe:	Stem Cell Research & Therapy
Schlagworte:	Mesenchymal stromal cells Secretome Intervertebral disc Conditioned medium Intervertebral disc degeneration
Online-Zugang:	https://doi.org/10.1186/s13287-020-02062-2
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