Computation suggests that the cell adhesion sub-proteome is enriched for sites of pH-dependence and charge burial.
Prediction of protein pH-dependence is generally made for individual proteins or pathways, and is also increasingly being used to aid protein functional design. Combining high-throughput pKa prediction methods with AlphaFold models allows pH-dependence to be studied across a proteome. Here, two meth...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2025-01-01
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| Seria: | PLoS ONE |
| Dostęp online: | https://doi.org/10.1371/journal.pone.0338186 |
| Etykiety: |
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