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Computation suggests that the cell adhesion sub-proteome is enriched for sites of pH-dependence and charge burial.

Prediction of protein pH-dependence is generally made for individual proteins or pathways, and is also increasingly being used to aid protein functional design. Combining high-throughput pKa prediction methods with AlphaFold models allows pH-dependence to be studied across a proteome. Here, two meth...

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Xehetasun bibliografikoak
Egile Nagusiak: Shalaw Sallah, Jim Warwicker
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2025-01-01
Saila:PLoS ONE
Sarrera elektronikoa:https://doi.org/10.1371/journal.pone.0338186
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