Potential Broad Spectrum Inhibitors of the Coronavirus 3CLpro: A Virtual Screening and Structure-Based Drug Design Study

Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory syndrome (MERS) less than 10 years later demonstrates the potential of coron...

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Detalles Bibliográficos

Autores principales:	Michael Berry, Burtram C. Fielding, Junaid Gamieldien
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2015-12-01
Colección:	Viruses
Materias:	human coronaviruses molecular docking 3CLpro virtual screening structure-based drug design molecular dynamics
Acceso en línea:	http://www.mdpi.com/1999-4915/7/12/2963
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