Impact of anesthetics on rat hippocampus and neocortex: A comprehensive proteomic study based on label-free mass spectrometry

Anesthesia is regarded as an important milestone in medicine. However, the negative effect on memory and learning has been observed. In addition, the impact of anesthetics on postoperative cognitive functions is still discussed. In this work, in vivo experiment simulating a general anesthesia and IC...

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Detalhes bibliográficos

Principais autores:	David Astapenko, Marie Vajrychova, Ivo Fabrik, Rudolf Kupcik, Kristyna Pimkova, Vojtech Tambor, Vera Radochova, Vladimir Cerny
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-03-01
coleção:	Heliyon
Assuntos:	Label-free proteomics Anesthetics Neocortex Hippocampus Long-term potentiation NMDAR
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024036697
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