Impact of anesthetics on rat hippocampus and neocortex: A comprehensive proteomic study based on label-free mass spectrometry

Anesthesia is regarded as an important milestone in medicine. However, the negative effect on memory and learning has been observed. In addition, the impact of anesthetics on postoperative cognitive functions is still discussed. In this work, in vivo experiment simulating a general anesthesia and IC...

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Главные авторы:	David Astapenko, Marie Vajrychova, Ivo Fabrik, Rudolf Kupcik, Kristyna Pimkova, Vojtech Tambor, Vera Radochova, Vladimir Cerny
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2024-03-01
Серии:	Heliyon
Предметы:	Label-free proteomics Anesthetics Neocortex Hippocampus Long-term potentiation NMDAR
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2405844024036697
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